How much does a Colonoscopy with biopsy cost?

Colonoscopy with biopsy · CPT 45380 · A colonoscopy with biopsy examines the colon and samples tissue for analysis.

The typical insurer-negotiated price for a Colonoscopy with biopsy is about $1,649, with most between $862 and $2,539 ($1,644 cash/self-pay). Based on published rates from 2,781 U.S. hospitals. Hospital list charges run about $3,003 — roughly 1.8× higher.

Insurer-negotiated
$1,649
typical · $862$2,539
Cash / self-pay
$1,644
typical cash price
Hospital list charge
$3,003
1.8× the negotiated rate

Source: medians across 2,781hospitals' machine-readable price files (required by federal law since 2021). Figures are estimates and vary by hospital, region, insurer, and plan.

Colonoscopy with biopsy cost — frequently asked questions

How much does a Colonoscopy with biopsy cost with insurance?

The typical insurer-negotiated rate for a Colonoscopy with biopsy is about $1,649, with most falling between $862 and $2,539, based on published rates from 2,781 U.S. hospitals. What you actually pay depends on your plan's deductible and coinsurance.

How much does a Colonoscopy with biopsy cost without insurance?

Cash or self-pay prices for a Colonoscopy with biopsy run around $1,644. Uninsured patients are often billed the much higher hospital "list" charge first (about $3,003), so it's worth asking for the cash or self-pay rate and negotiating.

Why is my hospital Colonoscopy with biopsy bill so much higher?

Hospital "list" (chargemaster) prices for a Colonoscopy with biopsy run about $3,003 — roughly 1.8× the $1,649 insurers actually pay. The list price is a starting point almost no one pays; the negotiated and cash rates are the realistic benchmark.

Can I negotiate the cost of a Colonoscopy with biopsy?

Yes. If you were charged well above the typical negotiated rate (about $1,649), that gap is negotiable. Upfronte audits your bill against real hospital pricing data and can negotiate it down on your behalf — no savings, no fee.

Were you charged more than $1,649?

Upload your bill and Upfronte will check it against real hospital pricing data and negotiate overcharges. No savings, no fee.

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Colonoscopy with biopsy cost by location

Median negotiated prices for specific states and metro areas.

Metro areas

States

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